Histamin Intolerances, Lactose Intolerances, and Gluten Sensitivity
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| FULL RANGE OF PRODUCTS Click here |
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| HISTAMIN INTOLERANCE |
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| Histamine |
Histamine
intolerance is a clinical picture that has been observed with
increasing frequency in recent years. Histamine is an important
mediator of many biological reactions in the body, notably of allergic
and pseudoallergic reactions. The pathological basis of this condition
is an imbalance between the amount of histamine present and histamine
degradation by DAO. If the functionality/activity of DAO is reduced,
the individual histamine tolerance threshold is exceeded, inducing
histamine-mediated symptoms.
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| Assay |
| Histamin |
| Histamine Release - supplementary kit |
Histamine Research
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Histamine Cell Culture
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Histamine Stool
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Diamine Oxidase (DAO)
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| The enzyme diamine oxidase (DAO)
degrades amines such as spermidine, putrescine and histamine.
Therefore, DAO plays a central role in physiology: a lack of DAO can
trigger histamine intolerance with concentration dependent
histaminergic symptoms. These include allergic diseases such as
rhinitis and asthma. We now offer exclusively polyclonal antibodies and
ELISA Kit for research of the molecular mechanisms involved in
development and manifestation of histamine intolerance. |
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Antibody against
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Diamine oxidase, human
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| Diamine oxidase, human |
| Diamine oxidase, human |
| Diamine oxidase, human |
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| Assay |
Diamine Oxidase (DAO) ELISA
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| LACTOSE INTOLERANCE |
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| Laktase |
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with lactose intolerance are not able to digest milk sugar (lactose)
taken in with food. The most important reason is founded in a genetical
lack of the enzyme lactase which is responsible for the degradation of
milk sugar in the organism. This common gene defect is very easy to
detect by analyzing the T/C base replacement at position -13910 from
the regulatory region of the lactase gene. If this point mutation is
homozygous, a lactase deficiency and subsequent lactose intolerance is
predetermined. The Kit MutaGEL Laktase allows the detection of the
common T13910C polymorphism in the lactase gene LCT. |
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| Assay |
| MutaGEL Laktase |
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| GLUTEN SENSITIVITY |
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Transglutaminase (TG)
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The target antigen to detect antibodies for celiac disease is the tissue transglutaminase
(tTG,TGc, TGII). Meanwhile, the measurement of tTG IgA antibodies
represents the golden standard for celiac diseases in routine
laboratories. Assay built on recombinant human tTG show the highest
clinical sensitive and specific data.
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| Antibody against |
Cat. N° |
Host |
Form |
Applications |
Quantity |
| Human Tissue Transglutaminase (TGc) |
IMM-AK3010.1 |
Rabbit
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Serum |
ELISA
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20 uL |
Human Tissue Transglutaminase (TGc)
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IMM-AK3010.2 |
Rabbit
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Serum |
ELISA |
100 uL
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Human Epidermal Transglutaminase (TGe)
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IMM-AP1005.1
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Rabbit
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Serum |
E, IM, C
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20 uL
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| Human Epidermal Transglutaminase (TGe) |
IMM-AP1005.2
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Rabbit
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Serum
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E. IM, C
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100 uL
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| Antigen |
Cat. N° |
Form |
Quantity |
| Human Tissue Transglutaminase (TGc) |
IMM-AK3010AG.1 |
Recombinant Protein
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100 ug
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| Human Tissue Transglutaminase (TGc) |
IMM-AK3010AG.2 |
Recombinant Protein |
1 mg
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| Human Epidermal Transglutaminase (TGe) |
IMM-AP1005AG.1 |
Recombinant Protein |
100 ug
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| Human Epidermal Transglutaminase (TGe) |
IMM-AP1005AG.2 |
Recombinant Protein |
1 mg |
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| Assay |
Cat. N° |
Method |
Matrix/Volume |
Incubation |
Calibrator |
| anti-Human Tissue Transglutaminase IgG (anti-htTG IgG) |
IMM-K9398 |
ELISA 96w
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Serum,Plasma (50uL)
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2h
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| anti-Human Tissue Transglutaminase IgA (anti-htTG IgA) |
IMM-K9399 |
ELISA 96w |
Serum,Plasma (100uL) |
1h; 1h; 15min
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cut off
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| anti-Human Epidermal Transglutaminase IgA (anti-heTG IgA) |
IMM-K9396 |
ELISA 96w |
Serum,Plasma (100uL) |
1h; 1h; 30min |
cut off |
| anti-Human Tissue Transglutaminase sIgA (anti-htTG sIgA) |
IMM-K9393 |
ELISA 96w |
Stool (100uL) |
1h; 1h; 15-25min |
cut off |
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| Gliadin |
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It was found out that anti-endomysial antibodies are produced by the intestinal mucosa from CD patiens (Picarelli et
al. 2002). Moreover, it was reported, that CD patiens with TG-negative
serum results were TG-positively tested when stool samples were
analysed. Consequently, analysis of stool samples are recomended for an
additional information.
Anti-gliadin-sIgA/IgA may be detected in stool with our ELISA.
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| Assay |
Cat. N° |
Method |
Matrix |
Incubation |
Calibrator |
| anti-Gliadin sIgA |
IMM-K9311 |
ELISA 96w |
Stool |
1h; 1h; 15-25min |
cut off |
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| HLA DQ |
The MutaGEL HLA-DQ 2+8
test allows the individual HLA-DQ genotyping by amplification of the
encoding allels (for 24 determinations). For this purpose only a small
sample of EDTA-blood is necessary for the preliminary extraction of DNA
(reagents not included). The subsequent processing with molecular
biological methods leads to specific amplification products detectable
by gel electrophoresis.
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| Assay |
Cat. N° |
Method |
Matrix
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Volume |
| MutaGEL HLA-DQ 2+8 |
IMM-KE09020 |
PCR 24tests |
DNA (e.g whole blood, sputum)
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200 uL |
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For further info CONTACT US
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