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Food Intolerance
Histamin Intolerances, Lactose Intolerances, and Gluten Sensitivity 
 
 

 
 HISTAMIN INTOLERANCE

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Histamine
Histamine intolerance is a clinical picture that has been observed with increasing frequency in recent years. Histamine is an important mediator of many biological reactions in the body, notably of allergic and pseudoallergic reactions. The pathological basis of this condition is an imbalance between the amount of histamine present and histamine degradation by DAO. If the functionality/activity of DAO is reduced, the individual histamine tolerance threshold is exceeded, inducing histamine-mediated symptoms.
 
 Assay
Histamin
Histamine Release - supplementary kit
Histamine Research
Histamine Cell Culture
Histamine Stool
 
 
Diamine Oxidase (DAO)
The enzyme diamine oxidase (DAO) degrades amines such as spermidine, putrescine and histamine. Therefore, DAO plays a central role in physiology: a lack of DAO can trigger histamine intolerance with concentration dependent histaminergic symptoms. These include allergic diseases such as rhinitis and asthma. We now offer exclusively polyclonal antibodies and ELISA Kit for research of the molecular mechanisms involved in development and manifestation of histamine intolerance.
 
 Antibody against
Diamine oxidase, human
Diamine oxidase, human
Diamine oxidase, human
Diamine oxidase, human
 
 
 Assay
Diamine Oxidase (DAO) ELISA
 
 
 LACTOSE INTOLERANCE
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Laktase
Patients with lactose intolerance are not able to digest milk sugar (lactose) taken in with food. The most important reason is founded in a genetical lack of the enzyme lactase which is responsible for the degradation of milk sugar in the organism. This common gene defect is very easy to detect by analyzing the T/C base replacement at position -13910 from the regulatory region of the lactase gene. If this point mutation is homozygous, a lactase deficiency and subsequent lactose intolerance is predetermined. The Kit MutaGEL Laktase allows the detection of the common T13910C polymorphism in the lactase gene LCT.
 
 Assay
 MutaGEL Laktase
 
 

GLUTEN SENSITIVITY

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Celiac disease is both a disease of malabsorption—meaning nutrients are not absorbed properly—and an abnormal immune reaction to gluten. Celiac disease is genetic.

 

Transglutaminase (TG) The target antigen to detect antibodies for celiac disease is the tissue transglutaminase (tTG,TGc, TGII). Meanwhile, the measurement of tTG IgA antibodies represents the golden standard for celiac diseases in routine laboratories.

Assay built on recombinant human tTG show the highest clinical sensitive and specific data.

 

Deamidated gliadin peptide (DGP) antibodies (anti-DGP), IgA or IgG — may be positive in some people with celiac disease who are negative for anti-tTG, especially children less than 2 years old. It may sometimes be ordered with or following an anti-tTG test, especially if anti-tTG is negative. DGP IgG testing along with anti-tTG IgG is recommended by the American College of Gastroenterology for people who have low IgA or IgA deficiency. If the anti-DGP test is positive, it may be used to monitor celiac disease.

Zonulin is a protein that modulates the permeability of tight junctions between cells of the wall of the digestive tract. Zonulin has been implicated in the pathogenesis of coeliac disease and diabetes mellitus type 1.

 

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  Assay

 

Metodo 

Tissue Transglutaminase Ab IgA

 

ELISA 96T 

Tissue Transglutaminase Ab IgG

 

ELISA 96T 

Tissue Transglutaminase Ab Screen

 

ELISA 96T 

Anti-Human Epidermal Transglutaminase IgA (anti-heTG IgA)

 

ELISA 96T

DGP Ab IgA

 

ELISA 96T 

DGP Ab IgG

 

ELISA 96T

DGP Ab Screen

 

ELISA 96T 

Zonulin ELISA stool

 

ELISA 96T

Zonulin ELISA serum

 

ELISA 96T

 

 

 

MutaGEL HLA-DQ 2+8

 

PCR 24 test

 
   
   
   
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